Testing Status of 1,1,2-Trichloroethane 11620-S
CASRN: 79-00-5
Formula: C2-H3-Cl3
Synonyms/Common Names
- Vinyl trichloride
Short-Term Toxicity
- 14-Day (Gavage)
(C04579)
Completed
- Rats: Osborne Mendel; Mice: B6C3F1
- 13-Week (Gavage)
(C04579)
Completed
- Rats: Osborne Mendel; Mice: B6C3F1
- Dose: R: 0, 32, 316, M: 0, 56, 562 MG/KG/10 PER GROUP.
Long-Term Carcinogenicity
- 2-Year (Gavage)
(C04579)
Completed
- TR-074 (NIH Number: 78-1324)
(Peer Review Approval 01/18/1978A )
Bioassay of 1,1,2-Trichloroethane for Possible Carcinogenicity (CASRN 79-00-5) - Rats: Osborne Mendel; Mice: B6C3F1
- Carcinogenesis Results
- Male Rats Negative
- Female Rats Negative
- Male Mice Positive
- Female Mice Positive
- Dose: R: 0, 46, 92 (AVG), M: 0, 195, 390 (AVG) MG/KG/50 PER GROUP.
- TR-074 (NIH Number: 78-1324)
(Peer Review Approval 01/18/1978A )
Genetic Toxicology
- Drosophila
(915310)
Completed
- Citation: Foureman, P., Mason, J.M., Valencia, R., Zimmering, S. Chemical Mutagenesis Testing in Drosophila. IX. Results of 50 coded compounds tested for the National Toxicology Program. Environ. Molec. Mutagen. Vol. 23 (1994) 51-63
- Reciprocal Translocation/Sex-Linked Recessive Lethal Negative
- In Vitro Cytogenetics (CA/SCE)
(834917)
Completed
- Sister Chromatid Exchange Positive
- Chromosome Aberrations Positive
- Salmonella
(590584)
Completed
- Negative
- Salmonella
(624635)
Completed
- Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelmans, K. Salmonella mutagenicity tests. IV. Results from the testing of 300 chemicals Environ. Molec. Mutagen. Vol. 11 (Suppl 12) (1988) 1-158
- Negative
- Salmonella
(946672)
Completed
- Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelmans, K. Salmonella mutagenicity tests. IV. Results from the testing of 300 chemicals Environ. Molec. Mutagen. Vol. 11 (Suppl 12) (1988) 1-158
- Negative
- Salmonella
(A38940)
Completed
- Equivocal