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Testing Status of Lead sulfide 1314870

 

CASRN: 1314-87-0

Formula: Pb-S

Synonyms/Common Names

  • Plumbous sulfide

Short-Term Toxicity

  • 4 weeks (Dosed-Feed)  (C88040)  Completed 
    • Rats: F344/N
    • Dose: MR: 0, 10, 30, OR 100 PPM; 10 PER GROUP.
  • 13 & 26 weeks (Dosed-Feed)  (C88040B)  Completed 
    • Rats: F344/N
    • Dose: RATS: MALE AND FEMALE 0, 10, 30, 100 PPM, 10/GROUP 30, 60, 90, 180 DAY SAC.

Special Studies

  • Absorption Disposition Metabolism Elimination (Dosed-Feed)  (S0265)  Completed 
    • Male Rats: F344/N
    • Dose: 10, 30, 100 PPM.
  • Absorption Disposition Metabolism Elimination (Dosed-Feed)  (S0477)  Completed 
    • Citation: Dieter MP, Matthews HB, Jeffcoat RA, Moseman RF. Comparison of lead bioavailability in F344 rats fed lead acetate, lead oxide, lead sulfide, or lead ore concentrate from Skagway, Alaska. J Toxicol Environ Health. 1993 May;39(1):79-93.Pubmed Abstract
    • Male Rats: F344/N
    • Dose: 0, 10, 30 OR 100 PPM.

Genetic Toxicology

  • Chromosome Aberrations  (A89452)  Completed 
    • Mice
    •  Negative 
  • Micronucleus  (A82989)  Completed 
    • Mice: B6C3F1
    • Male Negative 
  • Salmonella  (A87030)  Completed 
    •  Negative