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Pentamidine isethionate (140-64-7)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID5023796


Study Results


Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Pentamidine isethionate (140-64-7).
Micronucleus - Mice
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  • Male: Negative
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Pentamidine isethionate (140-64-7).
Mammalian Cell Cytogenetics
CA SCE
  • View
    • Weakly Positive
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Pentamidine isethionate (140-64-7).
Bacterial Mutagenicity
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  • Negative
View
  • Negative

Citation Information


NTP. Pentamidine isethionate (140-64-7). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


Phillips, M.D., Nascimbeni, B., Tice, R.R., and Shelby, M.D. Induction of MN in Mouse BM cells: An evaluation of nucleoside analogues used in the treatment of Aids. Environ. Molec. Mutag. Vol. 18 (1991) 168-183

Study Data


Genetic Toxicology Studies


Genetic Toxicity Evaluation of Pentamidine Isethionate (140-64-7) in Micronucleus Study 679589 in B6C3F1 Mice
Genetic Toxicity Evaluation of Pentamidine Isethionate in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 570969
Summary Data
Genetic Toxicity Evaluation of Pentamidine Isethionate in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A55199
Summary Data