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Testing Status of Aloin 15037


CASRN: 1415-73-2

Formula: C21H22O9

Synonyms/Common Names

  • 1,8-Dihydroxy-3-hydroxymethyl-10-(6-hydroxymethyl-3,4,5-trihydroxy-2-pyranyl)anthrone
  • 10-Glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)-9(10H)-anthracenone

Short-Term Toxicity

  • 13 weeks (Dosed-Water)  (C15037)  Completed 
    • Citation: Boudreau MD, Olson GR, Tryndyak VP, Bryant MS, Felton RP, Belan FA. From the cover: Aloin, a component of the aloe vera plant leaf, induces pathological changes and modulates the composition of microbiota in the large intestines of F344/N male rats. Toxicol Sci. 2017 Aug 1;158(2):302–318.
    • Rats: F344 (NCTR)
    • Dose: MR: 0, 6.95. 13.9, 27.8, 55.7, 111, 223, or 446 ppm; 10 per/group.