Skip to Main Navigation
Skip to Page Content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Testing Status of 2-((1-(4-Phenoxyphenoxy)propan-2-yl)oxy)pyridine 16011

 

CASRN: 95737-68-1

Formula: C20-H19-N-O3

Synonyms/Common Names

  • MPEP
  • MPPE
  • 2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine
  • Pyridine, 2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]-
  • Pyriproxyfen

Special Studies

  • GD 7 to GD 28 Preliminary Toxicokinetic Study (Gavage)  (K16011B)  Completed 
    • Female Rabbits
    • Dose: 0, 62.5, or 125 mg/kg/day.
  • GD 6 to GD 18 Toxicokinetic Study (Gavage)  (K16011)  Completed 
    • Pilot TK (Pilot Fetal Transfer Study on MPEP)
    • Rats: Harlan Sprague-Dawley
    • Dose: 0, 62.5, 250 mg/kg per day.

Organ Systems Toxicity

  • GD 6 to GD 21 Conventional Teratology (Gavage)  (R16011)  Completed 
    • Citation: National Toxicology Program (NTP). 2022. NTP developmental and reproductive toxicity technical report on the prenatal development studies of 2-((1-(4-phenoxyphenoxy)propan-2-yl)oxy)pyridine (CASRN 95737-68-1) in Sprague Dawley (Hsd:Sprague Dawley SD) rats and New Zealand White (Hra:NZW SPF) rabbits. Research Triangle Park, NC: National Toxicology Program. DART Report 07. https://doi.org/10.22427/NTP-DART-07
    • Female Rats: Hsd:Sprague Dawley SD
    • Dose: Rat: 0, 62.5, 125, 250, or 500 mg/kg/day.
  • GD 7 to GD 28 Conventional Teratology (Gavage)  (R16011B)  Completed 
    • Citation: National Toxicology Program (NTP). 2022. NTP developmental and reproductive toxicity technical report on the prenatal development studies of 2-((1-(4-phenoxyphenoxy)propan-2-yl)oxy)pyridine (CASRN 95737-68-1) in Sprague Dawley (Hsd:Sprague Dawley SD) rats and New Zealand White (Hra:NZW SPF) rabbits. Research Triangle Park, NC: National Toxicology Program. DART Report 07. https://doi.org/10.22427/NTP-DART-07
    • Female Rabbits: New Zealand White
    • Dose: 0, 62.5, 125, 250, or 500 mg/kg/day.
  • GD 7 to GD 28 Conventional Teratology (Gavage)  (R16011D)  Completed 
    • Citation: National Toxicology Program (NTP). 2022. NTP developmental and reproductive toxicity technical report on the prenatal development studies of 2-((1-(4-phenoxyphenoxy)propan-2-yl)oxy)pyridine (CASRN 95737-68-1) in Sprague Dawley (Hsd:Sprague Dawley SD) rats and New Zealand White (Hra:NZW SPF) rabbits. Research Triangle Park, NC: National Toxicology Program. DART Report 07. https://doi.org/10.22427/NTP-DART-07
    • Female Rabbits: New Zealand White
    • Dose: 0, 62.5, 125, 250 mg/kg/day.
  • 28 days Immunotoxicity (Gavage)  (I16011)  Data in Review 
    • Female Rats: Harlan Sprague-Dawley
    • Dose: 0, 63, 125, 250, or 500 mg/kg/day.
  • 28 days Immunotoxicity (Gavage)  (I16011HR)  Data in Review 
    • Female Rats: Harlan Sprague-Dawley
    • Dose: 0, 63, 125, 250, or 500 mg/kg/day.
  • GD 7 to GD 28 Teratology Pilot Studies (Gavage)  (R16011C)  Completed 
    • Citation: National Toxicology Program (NTP). 2022. NTP developmental and reproductive toxicity technical report on the prenatal development studies of 2-((1-(4-phenoxyphenoxy)propan-2-yl)oxy)pyridine (CASRN 95737-68-1) in Sprague Dawley (Hsd:Sprague Dawley SD) rats and New Zealand White (Hra:NZW SPF) rabbits. Research Triangle Park, NC: National Toxicology Program. DART Report 07. https://doi.org/10.22427/NTP-DART-07
    • Female Rabbits: New Zealand White
    • Dose: 0, 300, 400 and 500 mg/kg/day.