Skip to Main Navigation
Skip to Page Content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.


The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Testing Status of 2',3'-Didehydro-3'-deoxythymidine 3056175


CASRN: 3056-17-5

Formula: C10-H12-N2-O4

Synonyms/Common Names

  • D4T
  • D 4T
  • Stavudine

Special Studies

  • Toxicokinetic Study (Gavage)  (K3056175)  Completed 
    • Mice: C57BL/6J (Jackson)
    • Dose: 500 mg/kg.

Genetic Toxicology

  • In Vitro Cytogenetics (CA/SCE)  (665471)  Completed 
    • Sister Chromatid Exchange Positive 
    • Chromosome Aberrations Positive 
  • Micronucleus  (537402)  Completed 
    • Citation: Phillips, M.D., Nascimbeni, B., Tice, R.R., and Shelby, M.D. Induction of MN in Mouse BM cells: An evaluation of nucleoside analogues used in the treatment of Aids. Environ. Molec. Mutag. Vol. 18 (1991) 168-183
    • Mice: B6C3F1
    • Male Positive 
  • Salmonella  (420717)  Completed 
    •  Weakly Positive 
  • Salmonella  (A41441)  Completed 
    •  Negative 

Organ Systems Toxicity

  • Immunotoxicity (Gavage)  (IMM90016)  Completed 
    • Female Mice: C57BL/6 And DBA/2
    • Dose: 0, 125, 250, 500 MG/KG.