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Testing Status of Azathioprine C03474

 

CASRN: 446-86-6

Formula: C9-H7-N7-O2-S

Synonyms/Common Names

  • NSC 39084

Short-Term Toxicity

  • 14-Day (Intraperitoneal Injection)  (C03474)  Completed 
    • Rats: Sprague Dawley; Mice: Swiss
  • 13-Week (Intraperitoneal Injection)  (C03474)  Completed 
    • Rats: Sprague Dawley; Mice: Swiss

Long-Term Carcinogenicity

  • 2-Year (Intraperitoneal Injection)  (C03474)  Completed 
    •   (Peer Review Approval NA) Citation: EK Weisburger, Bioassay Program for Carcinogenic Hazards of Cancer Chemotherapeutic Agents. Cancer 40:1935-1949 (1977)
    • Rats: Sprague Dawley; Mice: Swiss
    • Dose: R: 0, 18, 37, M: 0, 7.5, 15.30 MG/KG/25 PER GROUP.

Genetic Toxicology

  • Salmonella  (850790)  Completed 
    • Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelman, K. Salmonella Mutagenicity Tests V. Results from the Testing of 311 Chemicals Environ. Molec. Mutagen. Vol. 19 (Suppl 21) (1992) 2-141
    •  Positive