Testing Status of Flutamide M010040

CASRN: 13311-84-7

Formula: C11-H11-F3-N2-O3

Synonyms/Common Names

• Eulexin
• 2-Methyl-N-[4'-nitro-3'-(trifluoromethyl)phenyl]propanamide
• M-Propionotoluidide, alpha, alpha, alpha-trifluoro-2-methyl-4'-nitro- (8CI)

Short-Term Toxicity

• 4 days (Gavage)  (C01040)  Completed 
  • Liver Targeted Testing study of Toxcast Chemicals
  • Rats: Harlan Sprague-Dawley
  • Dose: Male rats: 0, 10 mg/kg/day.

Organ Systems Toxicity

• Continuous Breeding (Legacy) (Gavage)  (RACB20107B)  Completed 
  • Male and Female Rats: SD & Wistar
  • Dose: 50 MG/KG DAY.

Toxicogenomics

• 4 days Microarray Analysis (Gavage)  (T01040)  Completed 
  • Liver Targeted Testing study of Toxcast Chemicals
  • Rats: Harlan Sprague-Dawley
  • Dose: not provided; 5 rats.