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Testing Status of Prilocaine hydrochloride M010094

 

CASRN: 1786-81-8

Formula: C13-H20-N2-O.Cl-H

Synonyms/Common Names

  • alpha-Propylamino-2'-methylpropionanilide hydrochloride
  • Citanest
  • N-(2-Methylphenyl)-2-(propylamino)-propanamide hydrochloride

Special Studies

  • Absorption Distribution Metabolism Excretion (Gavage)  (S0839)  Completed 
    • Citation: Sanders JM, Abu Shakra A, Burka LT, Cunningham, ML. Mutagenicity studies of urinary metabolites from rats treated orally with local anesthetics. Environmental Mutagen Society 34th Annual Meeting, May 10–14, 2003, Miami Beach, Florida. Program Chair: David A. Eastmond, Ph.D. Environ. Mol. Mutagen. 2003;41(3):190–204. doi: 10.1002/em.10147
    • Male Rats: F344/N
    • Dose: 100 mg/kg.

Genetic Toxicology

  • Micronucleus  (A30173)  Completed 
    • Mice: B6C3F1
    • Male Negative 
    • Female NA