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Testing Status of PCN 66/67 comparison study M030031

 

CASRN: PCNCOMPARISN

Secondary:

  • 103426-96-6 - 1,2,3,4,6,7-Hexachloronaphthalene (PCN 66)
  • 103426-97-7 - 1,2,3,5,6,7-Hexachloronaphthalene (PCN 67)
  • 1746-01-6 - Toxic equivalency factor evaluation (TCDD)
  • 1746-01-6 - TEF transgenics (TCDD)
  • 1746-01-6 - 2,3,7,8-Tetrachlorodibenzo-p-dioxin
  • 1746-01-6 - Transgenic Model Evaluation (2,3,7,8-Tetrachlorodibenzodioxin)

Short-Term Toxicity

  • 2 weeks (Gavage)  (C20306)  Report in Preparation 
    • Rats: Harlan Sprague-Dawley
    • Dose: Female rats only: PCN 66 and PCN 67: 0, 500, 1500, 5000, 50000, or 500000 ng/kg (5/group); TCDD: 1, 3, 10, 100, or 300 ng/kg (5/group).
  • 13 weeks (Gavage)  (C20306)  Report in Preparation 
    • Rats: F344/N; Rats: Harlan Sprague-Dawley; Rats: Sprague Dawley
    • Dose: Females only: PCN 66 and PCN 67: 0, 1000, 10000, 50000, 100000, or 200000 ng/kg; TCDD: 0, 10, 50, 100, or 200 ng/kg.