Testing Status of Sodium Tungstate Dihydrate M030038
CASRN: 10213-10-2
Formula: O4-W.2Na.2H2-O
Synonyms/Common Names
- Sodium tungstate dihydrate
- Tungstic acid, sodium salt, dihydrate
Short-Term Toxicity
- 13 weeks (Dosed-Water)
(C03038)
Report in Preparation
- Rats: Harlan Sprague-Dawley; Mice: B6C3F1
- Dose: 0, 125, 250, 500, 1000, or 2000 mg/L; 10/sex/species/dose.
Long-Term Carcinogenicity
- 2 years (Dosed-Water)
(C03038)
Report in Preparation
- Rats: Harlan Sprague-Dawley; Mice: B6C3F1
- Dose: R: 0, 250, 500, or 1000 mg/L; M: 0, 500, 1000, or 2000 mg/L; 50/sex/species/group.
Special Studies
- Absorption Disposition Metabolism Elimination (Gavage; Dosed-Water; Gavage; Dosed-Water)
(S0865)
Completed
- Citation: McDonald JD, Weber WM, Marr R, Kracko D, Khain H, Arimoto R. Disposition and clearance of tungsten after single-dose oral and intravenous exposure in rodents. J Toxicol Environ Health A. 2007 May 15;70(10):829-36.Pubmed Abstract
- Citation: Weber WM, Marr R, Kracko D, Gao Z, McDonald, JD. Disposition of tungsten in rodents after repeat oral and drinking water exposures. Toxicol. Environ. Chem. 2008 May-June;90(3):445-55
- Female Rats: F344/N; Female Mice: B6C3F1
- Dose: 0, 1, 10, 100 mg/kg gavage ; 560 mg/l drinking water.
Genetic Toxicology
- Comet Assay (Gavage)
(G03038E)
Completed
- Mice: B6C3F1/N
- Comet Assay (Gavage)
(G03038F)
Completed
- Rats: Harlan Sprague-Dawley
- Micronucleus
(G03038B)
Completed
- MM: B6C3F1
- Male Negative
- Female Negative
- Micronucleus
(G03038C)
Completed
- RR: Harlan Sprague-Dawley
- Male Negative
- Female Negative
- Salmonella
(G03038D)
Completed
- Negative
Organ Systems Toxicity
- 28 days Immunotoxicity (Dosed-Water)
(I03038)
Data in Review
- Female Mice: B6C3F1
- Dose: 0, 125, 250, 500, 1000 or 2000 mg/L.