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Testing Status of Fluorotelomer alcohol 8+2 (8:2 FTOH) M040003

 

CASRN: 678-39-7

Formula: C10-H5-F17-O

Synonyms/Common Names

  • 1H,1H,2H,2H-Perfluorodecanol
  • 1,1,2,2-Tetrahydroperfluoro-1-decanol

Special Studies

  • Preliminary Toxicokinetic Study (Gavage; Intravenous)  (K04003)  Completed 
    • Male and Female Rats: Harlan Sprague-Dawley
    • Dose: (gavage) 12, 40, 120, and 400 mg/kg. (intravenous) 12 and 40 mg/kg.
  • Toxicokinetic Study (Gavage; Intravenous)  (K04003B)  Completed 
    • Citation: Huang MC, Robinson VG, Waidyanatha S, Dzierlenga AL, DeVito MJ, Eifrid MA, Gibbs ST, Blystone CR. Toxicokinetics of 8:2 fluorotelomer alcohol (8:2-FTOH) in male and female Hsd:Sprague Dawley SD rats after intravenous and gavage administration. Toxicol Rep. 2019 Aug 20;6:924-932. doi: https://doi.org/10.1016/j.toxrep.2019.08.009. Erratum in: Toxicol Rep. 2020 Dec 22;8:28-29.Pubmed Abstract
    • Male and Female Rats: Harlan Sprague-Dawley
    • Dose: 12 mg/kg males; 40 mg/kg females. 12, 24, and 48 mg/kg males; 40, 80, and 160 mg/kg females.
  • Toxicokinetic Study (Gavage; Intravenous; Gavage)  (K10259)  Completed 
    • Female Rats: Fischer 344; Male Rats: Fischer 344; Female Rats: Fischer 344; Male Rats: Fischer 344
    • Dose: 12 mg/kg males; 40 mg/kg females. 12, 24, and 48 mg/kg males; 40, 80, and 160 mg/kg females.

Genetic Toxicology

  • Salmonella  (A74889)  Completed 
    •  Negative