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Diquat dibromide monohydrate (6385-62-2)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID7031248

Study Results

Genetic Toxicology

An overview of Genetic Toxicology In Vitro Micronucleus study conclusions related to Diquat dibromide monohydrate (6385-62-2).
In Vitro Micronucleus
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  • Positive
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Diquat dibromide monohydrate (6385-62-2).
Bacterial Mutagenicity
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  • Negative

Citation Information

NTP. Diquat dibromide monohydrate (6385-62-2). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications

Evaluation of the herbicide glyphosate, (aminomethyl)phosphonic acid, and glyphosate-based formulations for genotoxic activity using in vitro assays Stephanie L. Smith-Roe, Carol D. Swartz, Asma Rashid, Nicholas C. Christy, Jamie E. Sly, Xiaoqing Chang, Nisha S. Sipes, Keith R. Shockley, Shawn F. Harris, Sandra J. McBride, Gary J. Larson, Bradley J. Collins, Esra Mutlu, Kristine L. Witt

Environmental and Molecular Mutagenesis: https://onlinelibrary.wiley.com/doi/10.1002/em.22534
DOI: https://doi.org/10.22427/NTP-DATA-002-02220-0014-0000-3

Two data values for one concentration in the 4 h +S9 experimental condition were corrected after a quality assurance audit. This finding did not impact the interpretation of the study.

Study Data

Protocol

Toxicity and Carcinogenicity Studies

6 - 48-Hour Evaluation of the Toxicity (C20513B) of Diquat Dibromide Monohydrate (6385-62-2) in F344 Rats Exposed via Intraperitoneal Injection. NTP Special Study
Individual Animal Data
Clinical Chemistry Reports
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of Diquat dibromide Monohydrate (6385-62-2) in Litron MultiFlow DNA Damage Assay (p53, gamma-H2AX, Phospho-Histone H3) Study G05037 in Human TK6 Cells
Summary Data
Genetic Toxicity Evaluation of Diquat dibromide monohydrate (6385-62-2) in Micronucleus Study G05037C in Human TK6 Cells
Summary and Detailed Data
Genetic Toxicity Evaluation of Diquat dibromide monohydrate (6385-62-2) in Salmonella/E. coli Mutagenicity Test or Ames Test. Study G05037B
Summary Data

NTP Data Collections