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Testing Status of 2',2'''-Dithiobisbenzanilide M060048

 

CASRN: 135-57-9

Formula: C26-H20-N2-O2-S2

Synonyms/Common Names

  • Benzamide, N,N'-(dithiodi-2,1-phenylene)bis-
  • Bis(2-benzamidophenyl) disulfide
  • 2,2'-Dibenzamidodiphenyl disulfide
  • DTBBA
  • o-(Benzoylamino)phenyl disulfide

Special Studies

  • Absorption Distribution Metabolism Excretion (Dermal; Intravenous; Gavage; in-vitro; Dermal; Gavage; Intravenous)  (K06048)  Completed 
    • Citation: Garner CE, Wegerski CJ, Doyle-Eisele M, McDonald JD, Sanders JM, Moeller BC, Waidyanatha S. Disposition and metabolism of 2',2'"-Dithiobisbenzanilide in rodents following intravenous and oral administration and dermal application. Toxicol Rep. 2020 Jul 23;7:883-892. doi: https://doi.org/10.1016/j.toxrep.2020.07.006.Pubmed Abstract
    • Male and Female Rats: Harlan Sprague-Dawley; Male and Female Rats: Sprague Dawley; Male and Female Mice: B6C3F1
    • Dose: (in-vitro) up to 1 mM [R]. 4 mg/kg [R,M]. 4, 40 mg/kg [R,M]. 4, 40, 400 mg/kg [R,M].

Genetic Toxicology

  • Salmonella  (G06048)  Completed 
    •  Negative