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Testing Status of ortho-Phthalaldehyde M070036


CASRN: 643-79-8

Formula: C8-H6-O2

Synonyms/Common Names

  • 1,2-Benzenedicarboxaldehyde
  • o-Phthaldialdehyde
  • Phthalic aldehyde

Short-Term Toxicity

  • 90 days (Inhalation)  (C20727)  Completed 
    • TOX-84 
      Toxicity Studies of o-Phthalaldehyde (CASRN 643-79-8) Administered by Inhalation to Sprague Dawley (Hsd:Sprague Dawley SD) Rats and B6C3F1/N Mice
    • Rats: Harlan Sprague-Dawley; Mice: B6C3F1
    • Dose: Highest conc is MACWA; R: 20/sex/conc; M: 10/sex/conc.

Genetic Toxicology

  • Comet Assay  (G07036D)  Completed 
    • Rats
  • Comet Assay  (G07036E)  Completed 
    • Mice
  • Micronucleus  (G07036B)  Completed 
    • Rats: Harlan Sprague-Dawley
    • Male Negative 
    • Female Negative 
  • Micronucleus  (G07036C)  Completed 
    • Mice: B6C3F1
    • Male Equivocal 
    • Female Negative 
  • Salmonella  (G07036)  Completed 
    •  Positive