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Testing Status of 1020 Long Multiwalled Carbon Nanotube M070062

 

CASRN: L-MWNT-1020

Short-Term Toxicity

  • 30 days (Inhalation)  (C07062)  Completed 
    • TOX-94 
      Toxicity Studies of 1020 Long Multiwalled Carbon Nanotubes (CASRN L-MWNT-1020) Administered by Inhalation to Sprague-Dawley Rats and B6C3F1/N Mice
    • Rats: Harlan Sprague-Dawley; Mice: B6C3F1
    • Dose: R&M: 0, 0.1, 0.3, 1, 3, 10 mg/m3; 35 sex/species.
  • 30 days (Inhalation)  (C07062B)  Data in Review 
    • Rats: Harlan Sprague-Dawley; Mice: B6C3F1/N
    • Dose: Female rats (N = 72/exp. group) and mice (N = 48/exp. group) shipped to immunotoxicity contract lab (exp. concs = 0, 0.06, 0.2, or 0.6 mg/m3).

Long-Term Carcinogenicity

  • 2 years (Inhalation)  (C07062B)  On Test 
    • Rats: Harlan Sprague-Dawley; Mice: B6C3F1/N
    • Dose: 0, 0.06, 0.2, or 0.6 mg/m3.

Genetic Toxicology

  • Micronucleus (Inhalation)  (G07062)  Completed 
    • Female
    • Rats: Harlan Sprague-Dawley
  • Micronucleus (Inhalation)  (G07062B)  Completed 
    • Female
    • Mice: B6C3F1/N

Organ Systems Toxicity

  • 30 days Immunotoxicity (Inhalation)  (I07062)  Report in Preparation 
    • Female Rats: Harlan Sprague-Dawley
    • Dose: 0, 0.06, 0.2, or 0.6 mg/m3.
  • 30 days Immunotoxicity (Inhalation)  (I07062B)  Report in Preparation 
    • Female Mice: B6C3F1
    • Dose: 0, 0.06, 0.2, or 0.6 mg/m3.
  • 90 days Immunotoxicity (Inhalation)  (I07062C)  Report in Preparation 
    • Female Mice: B6C3F1
    • Dose: 0, 0.06, 0.2, or 0.6 mg/m3.