Skip to Main Navigation
Skip to Page Content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Testing Status of Ethinyl estradiol M200009

 

CASRN: 57-63-6

Formula: C20-H24-O2

Synonyms/Common Names

  • 19-Norpregna-1,3,5(10)-trien-20-yne-3,17-diol, (17alpha)-

Short-Term Toxicity

  • 5 days (Gavage)  (C20009B)  On Test 
    • 5-Day Transcriptomic Dose-Response Studies
    • Rats: Harlan Sprague-Dawley
    • Dose: Female rats: 0, 0.02, 0.067, 0.2, 0.6, 1.8, 5.4, 16.2, or 48.6 mcg/kg; N=4. Male rats: 0, 0.02, 0.067, 0.2, 0.6, 1.8, 5.4, 16.2, or 48.6 mcg/kg; N=4.

Genetic Toxicology

  • Micronucleus  (A39469)  Completed 
    • Mice: FVB/N
    • Male Negative 
    • Female Negative 
  • Micronucleus  (A51448)  Completed 
    • Mice: FVB/N
    • Male Negative 
    • Female Negative 
  • Micronucleus  (A93135)  Completed 
    • Mice: Tg.AC (FVB/N) Homozygous
    • Male Negative 
    • Female Negative 
  • Micronucleus  (A99151)  Completed 
    • Mice: Tg.AC (FVB/N) Homozygous
    • Male Negative 
    • Female Negative 
  • Salmonella  (018582)  Completed 
    • Citation: Dunkel, V., Zeiger, E., Brusick, D., McCoy, E., McGregor, D., Mortelmans, K., Rosenkranz, H., and Simmon, V. (1984) Reproducibility of microbial mutagenicity assays. I. Tests with Salmonella typhimurium and Escherichia coli using a standardized protocol. Environ. Mutagen. 6 (Suppl. 2): 1-251.
    • Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelmans, K. Salmonella mutagenicity tests. IV. Results from the testing of 300 chemicals Environ. Molec. Mutagen. Vol. 11 (Suppl 12) (1988) 1-158
    •  Negative 
  • Salmonella  (N-9099)  Completed 
    • Citation: Dunkel, V., Zeiger, E., Brusick, D., McCoy, E., McGregor, D., Mortelmans, K., Rosenkranz, H., and Simmon, V. (1984) Reproducibility of microbial mutagenicity assays. I. Tests with Salmonella typhimurium and Escherichia coli using a standardized protocol. Environ. Mutagen. 6 (Suppl. 2): 1-251.
    • Citation: Dunkel, V., Zeiger, E., Brusick, D., McCoy, E., McGregor, D., Mortelmans, K., Rosenkranz, H., and Simmon, V. Reproducibility of microbial mutagenicity assays. I. Tests with Salmonella typhimurium and Escherichia coli using a standardized protocol Environ. Mutagen. Vol. 6 (Suppl 2) (1984) 1-251

Toxicogenomics

  • 5 days Transcriptome Sequencing (Gavage)  (T20009)  On Test 
    • 5-Day Transcriptomic Dose-Response Studies
    • Rats: Harlan Sprague-Dawley