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Testing Status of Allylamine M200081

 

CASRN: 107-11-9

Formula: C3-H7-N

Synonyms/Common Names

  • 2-Propen-1-amine

Planned Carcinogenicity/Toxicity

  • 14 days (Gavage) Selected (C20081)  
    • Rats: Hsd:Sprague Dawley SD
    • Dose: 0, 0.5, 1, 5, 10, 25 mg/kg.
  • 1 day (Gavage) Selected (C20081B)  
    • Series Dose Escalation Cardiovascular Functional Assessment Study
    • Rats: Hsd:Sprague Dawley SD
    • Dose: Dose escalation, Single dose + recovery per dose level 0, 0.5, 1, 5, 10, 25 mg/kg.

Genetic Toxicology

  • Salmonella  (929007)  Completed 
    • Citation: Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K, Speck W. Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals. Environ Mutagen. 1987;9 Suppl 9:1-109.
    •  Negative 

Organ Systems Toxicity

  • 7 to 16 GD Conventional Teratology (Gavage)  (T0059)  Completed 
    • Female Rats: Sprague Dawley
    • Dose: 50 MG/KG/DAY.