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Testing Status of N-Methyl-2-pyrrolidone M20172

 

CASRN: 872-50-4

Formula: C5-H9-N-O

Synonyms/Common Names

  • 1-Methyl-2-pyrrolidinone (8CI)(9CI)

Special Studies

  • Absorption Distribution Metabolism Excretion (Gavage)  (S0263)  Completed 
    • Male Rats: F344/N
    • Dose: 5, 500 mg/kg.
  • Metabolism (Topical Application)  (S0200)  Completed 
    • Male Rats: F344/N
    • Dose: 0.2, 2.0, 20 mg/cm2.

Genetic Toxicology

  • Salmonella  (309283)  Completed 
    • Citation: Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
    •  Negative 
  • Salmonella  (750004)  Completed 
    • Citation: Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
    •  Negative