Testing Status of 1,2-Bis(2,4,6-tribromophenoxy)ethane M20292
CASRN: 37853-59-1
Formula: C14-H8-Br6-O2
Synonyms/Common Names
- Benzene, 1,1'-(1,2-ethanediylbis(oxy))bis(2,4,6-tribromo- (9CI)
- 1,2-Bis(2,4,6-tribromophenoxy)ethane
- BTBPE
- Firemaster 680
- Flame Retardant 2
Short-Term Toxicity
- 5 days (Gavage)
(C20292)
Report in Preparation
- Rats: Hsd:Sprague Dawley SD
- Dose: 0, 0.1, 1, 10, 100, or 1000 umol/kg; 6 males/group.
Special Studies
- Absorption Disposition Metabolism Elimination (Dosed-Feed)
(S0141)
Completed
- Citation: Nomeir AA, Markham PM, Ghanayem BI, Chadwick M. Disposition of the flame retardant 1,2-bis(2,4,6-tribromophenoxy)ethane in rats following administration in the diet. Drug Metab Dispos. 1993 Mar-Apr;21(2):209-14.Pubmed Abstract
- Male Rats: F344/N
- Dose: 0.05, 0.5, 5% IN FEED.
Genetic Toxicology
- Comet Assay
(G20292)
On Test
- Comet Assay
(G20292B)
On Test
- Salmonella
(068726)
Completed
- Citation: Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K, Speck W. Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals. Environ Mutagen. 1987;9 Suppl 9:1-109.
- Negative
Organ Systems Toxicity
- Neurotoxicology Assessment (Dosed-Feed)
(NTA94037)
Completed
- Citation: Animal Neurobehavioral Test Battery in NTP Assessment In: Advances in Neurobehavioral Toxicology: Applications in Environmental & Occupational Health (Barry L. Johnson, ED.), Lewis Publishers, Inc. pp. 403-418 (1990).
- Male and Female Rats/Mice: F344/N
Toxicogenomics
- 5 days Microarray Analysis (Gavage)
(T20292)
Report in Preparation
- Rats: Hsd:Sprague Dawley SD
- Dose: 0, 0.1, 1, 10, 100, or 1000 umol/kg; 6 males/group.