Testing Status of Aspartame M88167
CASRN: 22839-47-0
Related: TRANSGENIC MODEL EVALUATION II (ASPARTAME)
Formula: C14-H18-N2-O5
Synonyms/Common Names
- L-Phenylalanine, N-L-alpha-aspartyl-, 1-methyl ester
Genetic Toxicology
- Micronucleus
(A20159)
Completed
- Mice: P53 +/- (C57BL/6)
- Male Negative
- Female Positive
- Micronucleus
(A37530)
Completed
- Rats: Fischer 344
- Male Negative
- Micronucleus
(A56067)
Completed
- Mice: Tg.AC (FVB/N) Hemizygous
- Male Negative
- Female Negative
- Micronucleus
(A66023)
Completed
- Mice: P16(Ink4a)/(+/-) (C57BL/6)
- Male Negative
- Female Negative
- Micronucleus
(F37530)
Completed
- Rats: Fischer 344
- Male Negative
- Female NA
- Salmonella
(A13862)
Completed
- Negative
Organ Systems Toxicity
- Neurotoxicology Assessment (Gavage)
(NTA94035)
Completed
- Citation: Animal Neurobehavioral Test Battery in NTP Assessment In: Advances in Neurobehavioral Toxicology: Applications in Environmental & Occupational Health (Barry L. Johnson, ED.), Lewis Publishers, Inc. pp. 403-418 (1990).
- Male Rats: F344/N