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Testing Status of Interferon AD (AIDS Initiative) M890009



Short-Term Toxicity

  • 4 weeks (Subcutaneous Injection)  (C89003)  Completed 
    • Mice: B6C3F1
    • Dose: 500, 5000, 50000, OR 500000 UNITS DAY.

Long-Term Carcinogenicity

  • 2 years (Subcutaneous Injection)  (C89003)  Completed 
    • TR-469 (NIH Number: 99-3959)  (Peer Review Approval 12/11/1996A )
      Toxicology and Carcinogenesis Studies of AZT and AZT/ a-Interferon A/D in B6C3F1 Mice (Gavage Studies)
    • Mice: B6C3F1
    • Dose: MICE ONLY: 500 OR 5000 UNITS 3X/WEEK; 50/SEX/GROUP.