Testing Status of Ribavirin M890086

CASRN: 36791-04-5

Formula: C8-H12-N4-O5

Synonyms/Common Names

• 1H-1,2,4-Triazole-3-carboxamide, 1-beta-D-ribofuranosyl-(9CI)

Genetic Toxicology

• In Vitro Cytogenetics (CA/SCE)  (048858)  Completed 
  • Sister Chromatid Exchange Positive 
  • Chromosome Aberrations Negative 
• Micronucleus  (949294)  Completed 
  • Citation: Phillips, M.D., Nascimbeni, B., Tice, R.R., and Shelby, M.D. Induction of MN in Mouse BM cells: An evaluation of nucleoside analogues used in the treatment of Aids. Environ. Molec. Mutag. Vol. 18 (1991) 168-183
  • Mice: B6C3F1
  • Male Positive 
• Salmonella  (240437)  Completed 
  •  Negative 
• Salmonella  (A06370)  Completed 
  •  Negative 

Organ Systems Toxicity

• Immunotoxicity (Gavage)  (IMM90010)  Completed 
  • Female Mice: C57BL/6
  • Mice Female Positive 
  • Dose: 0, 75, 150, 300 MG/KG.