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Testing Status of 1,2,3,4-Butanetetracarboxylic acid M90009

 

CASRN: 1703-58-8

Formula: C8-H10-O8

Synonyms/Common Names

  • 1,1,4,4-Btca
  • Butanetetracarboxylic acid
  • Mesobutane-1,2,3,4-Tetracarboxylic Acid
  • Tetracarboxybutane

Genetic Toxicology

  • Salmonella  (782581)  Completed 
    •  Positive 

Organ Systems Toxicity

  • Continuous Breeding (Dosed-Water)  (RACB92142)  Completed 
    • Male and Female Rats: Sprague Dawley
    • Dose: N/A; N/A; N/A; N/A.
  • 6 to 19 GD Conventional Teratology (Gavage)  (TER97004)  Completed 
    • Female Rats: Sprague Dawley
    • Dose: 0, 250, 500, OR 1000 MG/KG/DAY.
  • Teratology Pilot Studies (Gavage)  (TRP92056)  Completed 
    • Rats
    • Dose: 0, 50, 200, 400, 600, 800 MG/KG/DAY.
  • Teratology Pilot Studies (Gavage)  (TRP92057)  Completed 
    • Rabbits: New Zealand White
    • Dose: 0, 50, 150, 300, 450, 600 MG/KG/DAY.
  • nonpregnant pilot animals dosed on 1 to 14 days and pregnant screen animals dosed on 6 to 19 GD Teratology Pilot Studies (Gavage)  (TRP97004)  Completed 
    • Female Rats: Sprague Dawley
    • Dose: 0, 50, 100, 500, 750 OR 1000 MG/KG/DAY (NONPREGNANT PILOT); 0, 62.5, 125, 250, 500 OR 1000 MG/KG/DAY (PREGNANT SCREEN).