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2-Methylimidazole (693-98-1)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID4022107


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Clear Evidence, Female, Rats
  • Some Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Some Evidence, Female, Mice
  • Some Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to 2-Methylimidazole (693-98-1).
Micronucleus - Mice
View
  • Male: Negative
View
  • Male: Positive
    Female: Positive
An overview of Genetic Toxicology Micronucleus Rats study conclusions related to 2-Methylimidazole (693-98-1).
Micronucleus - Rats
View
  • Male: Negative
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to 2-Methylimidazole (693-98-1).
Bacterial Mutagenicity
View
  • Negative

Citation Information


NTP. 2-Methylimidazole (693-98-1). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-516 Toxicology and Carcinogenesis Studies of 2-Methylimidazole (CASRN 693-98-1) in F344/N Rats and B6C3F1 Mice (Feed Studies)
TOX-67 Toxicity Studies of 2-Methylimidazole and 4-Methylimidazole Administered in Feed to F344/N Rats and B6C3F1Mice (CASRN 693-98-1 and 822-36-6)

Study Data


Toxicity and Carcinogenicity Studies


2-Week Evaluation of the Toxicity (C92012) of 2-Methylimidazole (693-98-1) in F344/N Rats Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C92012) of 2-Methylimidazole (693-98-1) in F344 Rats Exposed via Dosed Feed. NTP Special Study
2-Week Evaluation of the Toxicity (C92012) of 2-Methylimidazole (693-98-1) in B6C3F1 Mice Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C92012) of 2-Methylimidazole (693-98-1) in B6C3F1 Mice Exposed via Dosed Feed. NTP Special Study
3-Month Evaluation of the Toxicity (C92012) of 2-Methylimidazole (693-98-1) in F344/N Rats Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C92012) of 2-Methylimidazole (693-98-1) in B6C3F1 Mice Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity (C92012B) of 2-Methylimidazole (693-98-1) in F344/N Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity (C92012B) of 2-Methylimidazole (693-98-1) in B6C3F1 Mice Exposed via Dosed Feed

Genetic Toxicology Studies


Genetic Toxicity Evaluation of 2-Methylimidazole (693-98-1) in Micronucleus Study A05124 in B6C3F1 Mice
Genetic Toxicity Evaluation of 2-Methylimidazole (693-98-1) in Micronucleus Study A69851 in B6C3F1 Mice
Genetic Toxicity Evaluation of 2-Methylimidazole (693-98-1) in Micronucleus Study A84932 in F344 Rats
Genetic Toxicity Evaluation of 2-Methylimidazole in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A28742
Summary Data

Other NTP Studies


Toxicokinetic Evaluation (C92012B) of 2-Methylimidazole (693-98-1) in F344/N Rats and B6C3F1 Mice Exposed via Gavage or Intravenous Injection
Toxicokinetic Evaluation (K02825) of 2-Methylimidazole (DTXSID4022107) in Rat and Mouse