Testing Status of o-Chloropyridine M940010
CASRN: 109-09-1
Formula: C5-H4-Cl-N
Synonyms/Common Names
- 2-Chloropyridine
Short-Term Toxicity
- 2 weeks (Topical Application)
(C99002)
Completed
- Rats: F344/N; Mice: B6C3F1
- Dose: R&M: 0, 6.25, 12.5, 25, 50, OR 100 MG/KG; 10/SEX/DOSE.
- 13 weeks (Dosed-Water)
(C99002B)
Completed
- TOX-83 (NIH Number: 17-5945)
Toxicity Studies of o-Chloropyridine (CASRN 109-09-1) Administered by Dosed-Water to F344/N Rats and B6C3F1 Mice - Rats: F344/N; Mice: B6C3F1
- Dose: 0, 10, 30, 100, 300, or 1000 PPM; 10/sex/species.
- TOX-83 (NIH Number: 17-5945)
Special Studies
- Absorption Disposition Metabolism Elimination (Gavage; Topical Application; Intravenous; Intraperitoneal Injection)
(S0819)
Completed
- Male Rats: F344/N; Male Mice: B6C3F1
- Dose: 0.1, 1, 5, 10 mg/kg.
Genetic Toxicology
- Micronucleus
(A80857)
Completed
- Mice: B6C3F1
- Male Negative
- Female Negative
- Salmonella
(A14054)
Completed
- Positive
in vitro Testing
- Bovine Corneal Opacity and Premeability Assay (Gavage, Whole Body Exposure)
(IVT20004A)
Completed
- Rats/Mice: F344/N
- Dose-Response Cytotoxicity Assay Using the EpiDermTM Skin Model (Gavage)
(IVT20004B)
Completed
- Mice: B6C3F1/N
- Neutral Red Uptake Bioassay (Gavage)
(IVT20004C)
Completed
- Rats: Harlan Sprague-Dawley
- Cytotoxicity Assay Using MTT Reduction in Primary Rat Hepatocytes (Dosed-Feed)
(IVT20004D)
Completed
- Mice: B6C3F1 (NCTR)