Skip to Main Navigation
Skip to Page Content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Testing Status of Sodium arsenite M940036

 

CASRN: 7784-46-5

Formula: As-H-O2.Na

Synonyms/Common Names

  • Sodium meta-arsenite

Planned Carcinogenicity/Toxicity

  • 14 days (Gavage) Selected (C94036B)  
    • Rats: Hsd:Sprague Dawley SD
    • Dose: 0, 0.1, 0.5, 1, 2.5, 5 mg/kg.
  • 1 day (Gavage) Selected (C94036C)  
    • Series Dose Escalation Cardiovascular Functional Assessment Study
    • Rats: Hsd:Sprague Dawley SD
    • Dose: Dose escalation, Single dose + recovery per dose level 0, 0.1, 0.5, 1, 2.5, 5 mg/kg.

Special Studies

  • C. elegans  (S0946)  Completed 
    • C. elegans
  • acute Toxicokinetic Study (Gavage; Dosed-Water; Dosed-Feed)  (K94036)  Completed 
    • Rats: CD; Mice: CD-1 Reg.[Crl:CD1(ICR)]; Monkeys: Rhesus
    • Dose: Range finding: 0, 0.05, 0.1, or 0.2 mg/kg.

Genetic Toxicology

  • 3 days Comet Assay (Gavage)  (G94036)  Completed 
    • Rats: Sprague Dawley

Organ Systems Toxicity

  • 14 days Immunotoxicity (Subcutaneous Injection)  (IMM94004)  Completed 
    • Female Mice: B6C3F1
    • Dose: 0.01, 0.03, 0.06 MG/ML.