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Testing Status of Melatonin M940069

 

CASRN: 73-31-4

Formula: C13-H16-N2-O2

Synonyms/Common Names

  • Acetamide, N-(2-(5-methoxy-1H-indol-3-yl)ethyl)- (9CI)
  • 5-Methoxy-N-acetyltryptamine

Short-Term Toxicity

  • 1 day (Gavage)  (C96013A)  Completed 
    • Rats: F344/N; Rats: Long-Evans
    • Dose: 0, 5, OR 50 UG/KG AND 5, 50, OR 200 MG/KG; 7/GROUP.
  • 2 weeks (Gavage)  (C96013)  Completed 
    • Rats: F344/N; Rats: Long-Evans
    • Dose: 0, 5, OR 50 UG/KG AND 5, 50, OR 200 MG/KG; 10/SEX/GROUP -- 3 TIME POINTS.
  • 13 weeks (Gavage)  (C96013)  Completed 
    • Rats: F344/N; Rats: Long-Evans
    • Dose: 0, 5, OR 50 UG/KG AND 5, 50, OR 200 MG/KG; 10/SEX/GROUP -- 3 TIME POINTS.

Organ Systems Toxicity

  • 6 to 19 days GD Conventional Teratology (Gavage)  (TER96003)  Completed 
    • Female Rats: Sprague Dawley
    • Dose: 0, 50, 100, OR 200 MG/KG/DAY.
  • 6 to 19 days GD Teratology Pilot Studies (Gavage)  (TRP97001)  Completed 
    • Female Rats: Sprague Dawley
    • Dose: 0, 1, 10, 100, 150, OR 200 MG/KG/DAY.