Cyclophosphamide monohydrate (6055-19-2)
DOI: https://doi.org/10.22427/NTP-DATA-DTXSID6024888
Study Results
Genetic Toxicology
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| Micronucleus - Rats |
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| Mammalian Cell Cytogenetics | |
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| CA | SCE |
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| Drosophila Germ Cell Mutagenicity | |
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| SLRL | RT |
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| Bacterial Mutagenicity |
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Publications
Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
Yoon, J.S., Mason, J.M., Valencia, R., Woodruff, R.C., and Zimmering, S. Chemical mutagenesis testing in Drosophila: IV. Results of 45 coded compounds tested for the National Toxicology Program. Environ. Mutagen. Vol. 7 (1985) 349-367
Evaluation of Immunotoxicity of Sodium Metavanadate Following Drinking Water Exposure in Female B6C3F1/N Mice in a 28-day Study
Rachel Frawley, Victor J. Johnson, Gary R. Burleson, Keith R Shockley, Mark F. Cesta, Greg Travlos, Michelle Cora, Georgia Roberts, Dori Germolec
TOX-106 Vanadium Compounds (Sodium Metavanadate and Vanadyl Sulfate): Abstract for TOX-106
DOI: https://doi.org/10.22427/NTP-DATA-500-001-001-000-7
TOX-106 Vanadium Compounds (Sodium Metavanadate and Vanadyl Sulfate): Abstract for TOX-106
DOI: https://doi.org/10.22427/NTP-DATA-500-001-001-000-7
Study Data
Toxicity and Carcinogenicity Studies
26-Week Evaluation of the Toxicity (C97011A) of Cyclophosphide Monohydrate (6055-19-2) in FVB/N Mice Exposed via Topical Application. NTP Special Study
Pathology Tables
Individual Animal Data
- Male Individual Animal Hematology Data
- Male Individual Animal Organ Weight Data
- Female Individual Animal Hematology Data
- Female Individual Animal Organ Weight Data
Clinical Chemistry Reports
26-Week Evaluation of the Toxicity (C97011A) of Transgenic Model (Cyclophosphamide Monohydrate) (6055-19-2) in FVB/N Mice Exposed via Topical Application
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E05 - Clinical Observations Summary
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Neoplastic
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Neoplastic
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
26-Week Evaluation of the Toxicity (C97011B) of Cyclophosphide Monohydrate (6055-19-2) in FVB/N Mice Exposed via Gavage. NTP Special Study
Pathology Tables
Individual Animal Data
- Male Individual Animal Hematology Data
- Male Individual Animal Organ Weight Data
- Female Individual Animal Hematology Data
- Female Individual Animal Organ Weight Data
Clinical Chemistry Reports
26-Week Evaluation of the Toxicity (C97011B) of Transgenic Model (Cyclophosphamide Monohydrate) (6055-19-2) in FVB/N Mice Exposed via Gavage
Pathology Tables
- E01 - Animal Removal Summary By Treatment Group
- E03 - Growth Curves
- E04 - Mean Body Weights And Survival Table
- E05 - Clinical Observations Summary
- E12 - Animal History
- P02 - Incidence Rates Of Neoplasms By Anatomic Site (a)
- P03 - Incidence Rates Of Non-Neoplastic Lesions By Anatomic Site(a)
- P04 - Neoplasms By Individual Animal
- P05 - Incidence Rates Of Neoplasms By Anatomic Site (Systemic Lesions Abridged) (a)
- P07 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P09 - Non-Neoplastic Lesions By Individual Animal
- P11 - Statistical Analysis of Survival Data
- P15 - Slide/Block Inventory
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged)
- P18 - Incidence Rates Of Non-neoplastic Lesions By Anatomic Site (a) With Average Severity Grades[b]
- P40 - Survival Curves
Individual Animal Data
- P14 - Female,Male Individual Animal Pathology Data
- Male Individual Animal Body Weight Data
- Male Individual Animal Organ Weight Data
- Male Individual Animal Pathology Data Neoplastic
- Male Individual Animal Pathology Data Non Neoplastic
- Male Individual Animal Survival Data
- Male Individual Clinical Observations
- Female Individual Animal Body Weight Data
- Female Individual Animal Organ Weight Data
- Female Individual Animal Pathology Data Neoplastic
- Female Individual Animal Pathology Data Non Neoplastic
- Female Individual Animal Survival Data
- Female Individual Clinical Observations
26-Week Evaluation of the Toxicity (C97011A) of Transgenic Model (Cyclophosphamide Monohydrate) (6055-19-2) in Tg.AC (FVB/N) Mice Exposed via Topical Application. NTP Special Study
Pathology Tables
Individual Animal Data
- Male Individual Animal Hematology Data
- Male Individual Animal Organ Weight Data
- Female Individual Animal Hematology Data
- Female Individual Animal Organ Weight Data
Clinical Chemistry Reports
26-Week Evaluation of the Toxicity (C97011B) of Cyclophosphide Monohydrate (6055-19-2) in Tg.AC (FVB/N) Mice Exposed via Gavage. NTP Special Study
Pathology Tables
Individual Animal Data
- Male Individual Animal Hematology Data
- Male Individual Animal Organ Weight Data
- Female Individual Animal Hematology Data
- Female Individual Animal Organ Weight Data
Clinical Chemistry Reports
Genetic Toxicology Studies
Genetic Toxicity Evaluation of Cyclophosphamide Monohydrate (6055-19-2) in Micronucleus Study 813361 in B6C3F1 Mice
Genetic Toxicity Evaluation of Cyclophosphamide Monohydrate (6055-19-2) in Micronucleus Study A17052 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Cyclophosphamide Monohydrate (6055-19-2) in Micronucleus Study A25833 in F344 Rats
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Cyclophosphamide Monohydrate (6055-19-2) in Micronucleus Study A57498 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Cyclophosphamide Monohydrate (6055-19-2) in Micronucleus Study A91782 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Cyclophosphamide Monohydrate (6055-19-2) in Micronucleus Study A95722 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Cyclophosphamide Monohydrate (6055-19-2) in Micronucleus Study F25833 in F344 Rats
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Cyclophosphamide Monohydrate in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 101998
Summary Data
- G06 - Ames Summary Data (105 KB)
Genetic Toxicity Evaluation of Cyclophosphamide Monohydrate in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 122836
Summary Data
- G06 - Ames Summary Data (107 KB)