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Testing Status of Transgenic model evaluation II (Benzene) M990069

 

CASRN: 71-43-2

Formula: C6-H6

Synonyms/Common Names

  • Benzene (Transgenic model evaluation II)
  • Phenyl hydride

Short-Term Toxicity

  • 27 weeks (Gavage)  (C99034)  Completed 
    • GMM-08 (NIH Number: 08-4425)  (Peer Review Approval 08/28/2006A )
      Toxicology and Carcinogenesis Study of Benzene (CASRN 71-43-2) in Genetically Modified Haploinsufficient p16Ink4a/p19Arf Mice (Gavage Study)
    • Mice: P16(Ink4a)/(+/-) (C57BL/6)
    • Carcinogenesis Results
      • Male Clear Evidence 
      • Female No Evidence 
    • Dose: 0, 25, 50, 100, OR 200 MG/KG.