Skip to Main Navigation
Skip to Page Content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.


The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Testing Status of Transgenic model evaluation II (Phenolphthalein) M990071


CASRN: 77-09-8

Formula: C20-H14-O4

Synonyms/Common Names

  • 3,3-Bis(4-hydroxyphenyl)-1(3H)-isobenzofuranone
  • Phenolphthalein (Transgenic model evaluation II)

Short-Term Toxicity

  • 26 weeks (Dosed-Feed)  (C99036)  Completed 
    • GMM-12 (NIH Number: 08-5961)  (Peer Review Approval 08/28/2006A )
      Toxicology and Carcinogenesis Study of Phenolphthalein (CASRN 77-09-8) in Genetically Modified Haploinsufficient p16Ink4a/p19Arf Mice
    • Mice: P16(Ink4a)/(+/-) (C57BL/6)
    • Carcinogenesis Results
      • Male No Evidence 
      • Female No Evidence 
    • Dose: 0, 200, 375, 750, 3000, OR 12000 PPM.