U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.


The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.


ICCVAM Biennial Report 2020-2021

Biennial Progress Report 2020-2021 Interagency Coordinating Committee on the Validation of Alternative Methods


As an interagency committee of the U.S. federal government, ICCVAM takes a leadership role in promoting the use of NAMs. ICCVAM agencies promote new testing approaches through providing funding to support development of new methods, as well as through international interactions and collaborations.

Money bill and vaccine vial

Resources for Alternative Methods Development

ICCVAM agencies support alternative methods development through academic and small business grants.

Dr. Reinke at ECVAM workshop

International Interactions

ICCVAM and its member agencies interact with international partners to facilitate harmonization and regulatory acceptance.

Dr. Casey and other attedees from 2019 antibody workshop


ICCVAM agencies collaborate with stakeholders to advance development and use of alternative methods.