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Testing Status of Benzo(b)fluoranthene 11158-W

CASRN: 205-99-2

Formula: C20-H12

Synonyms/Common Names

  • 2,3-Benzfluoranthene

Genetic Toxicology

  • Salmonella  (204614)  Completed 
    • Citation: Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K. Salmonella mutagenicity tests: V. Results from the testing of 311 chemicals. Environ Mol Mutagen. 1992;19 Suppl 21:2-141. doi: 10.1002/em.2850190603
    •  Positive 

Organ Systems Toxicity

  • 28 days Immunotoxicity (Gavage)  (I11158)  Data in Review 
    • Citation: Hsieh JH, Sedykh A, Mutlu E, Germolec DR, Auerbach SS, Rider CV. Harnessing In Silico, In Vitro, and In Vivo Data to Understand the Toxicity Landscape of Polycyclic Aromatic Compounds (PACs). Chem Res Toxicol. 2021 Feb 15;34(2):268-285. https://doi.org/10.1021/acs.chemrestox.0c00213. Epub 2020 Oct 16.
    • Female Mice: B6C3F1
    • Dose: 0, 0.05, 0.16, 0.50, 1.6, 5.0, 16, 50 mg/kg.