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Testing Status of 2-((1-(4-Phenoxyphenoxy)propan-2-yl)oxy)pyridine 16011

 

CASRN: 95737-68-1

Formula: C20-H19-N-O3

Synonyms/Common Names

  • MPEP
  • MPPE
  • 2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine
  • Pyridine, 2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]-
  • Pyriproxyfen

Special Studies

  • GD 7 to GD 28 Preliminary Toxicokinetic Study (Gavage)  (K16011B)  Report in Preparation 
    • Female Rabbits
    • Dose: 0, 62.5, or 125 mg/kg/day.
  • GD 6 to GD 18 Toxicokinetic Study (Gavage)  (K16011)  Report in Preparation 
    • Pilot TK (Pilot Fetal Transfer Study on MPEP)
    • Rats: Harlan Sprague-Dawley
    • Dose: 0, 62.5, 250 mg/kg per day.

Organ Systems Toxicity

  • GD 6 to GD 21 Conventional Teratology (Gavage)  (R16011)  Report in Preparation 
    • Female Rats: Hsd:Sprague Dawley SD
    • Dose: Rat: 0, 62.5, 125, 250, or 500 mg/kg/day.
  • GD 7 to GD 28 Conventional Teratology (Gavage)  (R16011B)  Report in Preparation 
    • Female Rabbits: New Zealand White
    • Dose: 0, 62.5, 125, 250, or 500 mg/kg/day.
  • GD 7 to GD 28 Conventional Teratology (Gavage)  (R16011D)  Report in Preparation 
    • Female Rabbits: New Zealand White
    • Dose: 0, 62.5, 125, 250 mg/kg/day.
  • 28 days Immunotoxicity (Gavage)  (I16011)  Data in Review 
    • Female Rats: Harlan Sprague-Dawley
    • Dose: 0, 63, 125, 250, or 500 mg/kg/day.
  • 28 days Immunotoxicity (Gavage)  (I16011HR)  On Test 
    • Female Rats: Harlan Sprague-Dawley
    • Dose: 0, 63, 125, 250, or 500 mg/kg/day.
  • GD 7 to GD 28 Teratology Pilot Studies (Gavage)  (R16011C)  Report in Preparation 
    • Female Rabbits: New Zealand White
    • Dose: 0, 300, 400 and 500 mg/kg/day.