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Testing Status of Ephedra sinica extract 22004


CASRN: 85940-38-1

Synonyms/Common Names

  • Ephedra sinica Stapf

Planned Carcinogenicity/Toxicity

  • 14 days (Gavage) Selected (C22004)  
    • Rats: Hsd:Sprague Dawley SD
    • Dose: 0, 20, 40, 80, 160, 320 mg/kg.
  • 1 day (Gavage) Selected (C22004B)  
    • Series Dose Escalation Cardiovascular Functional Assessment Study
    • Rats: Hsd:Sprague Dawley SD
    • Dose: Dose escalation, Single dose + recovery per dose level 0, 20, 40, 80, 160, 320 mg/kg.

Genetic Toxicology

  • Micronucleus (in-vitro) Selected (G22004B)  
    • Human (Cell Lines)
  • Salmonella Selected (G22004)