Skip to Main Navigation
Skip to Page Content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Testing Status of Adriamycin C01514

 

CASRN: 23214-92-8

Formula: C27-H29-N-O11

Synonyms/Common Names

  • Doxorubicin
  • 14-Hydroxydaunomycin

Organ Systems Toxicity

  • Dominant Lethal (Female) (Dosed-Feed)  (DLF007)  Completed 
    • Citation: Generoso, W.M., Cain, K.T., Hughes, L.A., and Foxworth, L.B. A restudy of the efficacy of adriamycin in inducing dominant lethals in mouse spermatogonia stem cells. Mutation Res. 226:61-64 (1989).
    • Female Mice: SEC X C57BL
    • Mice Female Positive 
  • Dominant Lethal (Female) (Dosed-Feed)  (DLF008)  Completed 
    • Citation: Generoso, W.M., Cain, K.T., Hughes, L.A., and Foxworth, L.B. A restudy of the efficacy of adriamycin in inducing dominant lethals in mouse spermatogonia stem cells. Mutation Res. 226:61-64 (1989).
    • Female Mice: CH3 X C57BL
    • Mice Female Positive 
  • Dominant Lethal (Male) (Dosed-Feed)  (DLM006)  Completed 
    • Citation: Generoso, W.M., Cain, K.T., Hughes, L.A., and Foxworth, L.B. A restudy of the efficacy of adriamycin in inducing dominant lethals in mouse spermatogonia stem cells. Mutation Res. 226:61-64 (1989).
    • Male Mice: C3H X 101
    • Mice Male Negative