Testing Status of Vincamine M030032

CASRN: 1617-90-9

Formula: C21-H26-N2-O3

Synonyms/Common Names

• 14,15-Dihydro-14-hydroxy-,methyl ester, (3 alpha, 14 beta, 16 alpha) - 9CI
• Eburnameinie-14-carboxylic acid

Short-Term Toxicity

• 14 days (Gavage)  (C20610)  Completed 
  • 14-Day Range Finding Study
  • Mice: B6C3F1
  • Dose: 14-Day RF = Male and female mice: 0, 62.5, 125, 250, 500, or 1000 mg/kg.
• 2 weeks (Gavage)  (C20610)  Completed 
  • Pilot Perinatal Study
  • Rats: Harlan Sprague-Dawley
  • Dose: Pilot Perinatal = Female rats and pups: 0, 10, 30, 100, or 300 mg/kg.
• Range finding (Gavage)  (C20610)  Completed 
  • Perinatal Range Finding Study
  • Rats: Harlan Sprague-Dawley
  • Dose: Perinatal RF = Female rats: 0, 10, 30, 100, 300, or 1, 000 mg/kg.

Genetic Toxicology

• Salmonella  (A62042)  Completed 
  •  Negative