Testing Status of Sulfapyridine M90065

CASRN: 144-83-2

Formula: C11-H11-N3-O2-S

Synonyms/Common Names

• Benzenesulfonamide, 4-amino-N-(2-pyridinyl)- (9CI)

Genetic Toxicology

• Chromosome Aberrations  (673616)  Completed 
  • Mice
  •  Negative (Nonstandard Protocol) 
• Chromosome Aberrations  (A49990)  Completed 
  • Mice
  •  Negative (Nonstandard Protocol) 
• In Vitro Cytogenetics (CA/SCE)  (788992)  Completed 
  • Citation: Witt, K.L., Bishop, J.B., McFee, A.F., Kumarroo, V. Induction of chromosomal damage in mammalian cells in vitro and in vivo by Sulfapyridine or 5-aminosalicylic acid. Mutation Res. Vol. 283 (1992) 59-64
  • Sister Chromatid Exchange Positive 
  • Chromosome Aberrations Negative 
• Micronucleus  (163220)  Completed 
  • Mice: B6C3F1
  • Male Positive (Nonstandard Protocol) 
• Micronucleus  (673616)  Completed 
  • Mice: B6C3F1
  • Male Not a Valid Test 
• Micronucleus  (711865)  Completed 
  • Citation: Witt, K.L., Bishop, J.B., McFee, A.F., Kumarroo, V. Induction of chromosomal damage in mammalian cells in vitro and in vivo by Sulfapyridine or 5-aminosalicylic acid. Mutation Res. Vol. 283 (1992) 59-64
  • Rats: Fischer 344
  • Male Equivocal 
• Micronucleus  (A49990)  Completed 
  • Mice: B6C3F1
  • Male Positive 
  • Female Positive 
• Micronucleus  (A80525)  Completed 
  • Mice: B6C3F1
  • Male Positive 
• Salmonella  (635845)  Completed 
  •  Negative 
• Sister Chromatid Exchanges  (673616)  Completed 
  • Mice
  • Sister Chromatid  Positive (Nonstandard Protocol)