bis(2-Chloro-1-methylethyl) ether (108-60-1)
DOI: https://doi.org/10.22427/NTP-DATA-DTXSID4020167
Study Results
Chronic Bioassay Level of Evidence
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Genetic Toxicology
Rodent Cytogenetics | |
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CA | SCE |
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Mammalian Cell Mutagenicity |
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Mammalian Cell Cytogenetics | |
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CA | SCE |
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Drosophila Germ Cell Mutagenicity |
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SLRL |
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Bacterial Mutagenicity |
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Publications
TR-191
Bioassay of Technical Grade Bis(2-chloro-1-methylethyl) ether for Possible Carcinogenicity (CASRN 108-60-1)
TR-239
Carcinogenesis Bioassay of Bis(2-chloro-1-methylethyl)ether (~70) (CASRN 108-60-1) Containing 2-Chloro-1-methylethyl(2-chloropropyl)ether (~30) (CASRN 83270-31-9) in B6C3F1 Mice (Gavage Study)
Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
McGregor, D., Brown, A., Cattanach, P., Edwards, I., McBride, D., Riach, C., and Caspary, W. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay: III. 72 coded chemicals. Environ. Molec. Mutagen. Vol. 12 (1988) 85-154
Valencia, R., Mason, J.M., Woodruff, R.C., and Zimmering, S. Chemical mutagenesis testing in Drosophila: III. Results of 48 coded compounds tested for the National Toxicology Program. Environ. Mutagen. Vol. 7 (1985) 325-348
Galloway, S., Armstrong, M., Reuben, C., Colman, S., Brown, B., Cannon, C., Bloom, A., Nakamura, F., Ahmed, M., Duk, S., Rimpo, J., Margolin, B., Resnick, M., Anderson, B., and Zeiger, E. Chromosome aberration and sister chromatid exchanges in Chinese hamster ovary cells: Evaluations of 108 chemicals. Environ. Molec. Mutagen. Vol. 10 (Suppl 10) (1987) 1-176
Study Data
Toxicity and Carcinogenicity Studies
Evaluation of the Chronic Toxicity and Carcinogenicity of bis(2-Chloro-1-methylethyl) Ether (108-60-1) in Male F344 Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of bis(2-Chloro-1-methylethyl) Ether (108-60-1) in Female F344 Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of bis(2-Chloro-1-methylethyl) Ether (108-60-1) in Male B6C3F1 Mice Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of bis(2-Chloro-1-methylethyl) Ether (108-60-1) in Female B6C3F1 Mice Exposed via Gavage
Genetic Toxicology Studies
Genetic Toxicity Evaluation of bis(2-Chloro-1-methylethyl) Ether in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 035504
Summary Data
- G06 - Ames Summary Data (148 KB)
Genetic Toxicity Evaluation of bis(2-Chloro-1-methylethyl) Ether in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 082677
Summary Data
- G06 - Ames Summary Data (150 KB)
Genetic Toxicity Evaluation of bis(2-Chloro-1-methylethyl) Ether in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 175248
Summary Data
- G06 - Ames Summary Data (51 KB)
Genetic Toxicity Evaluation of bis(2-Chloro-1-methylethyl) Ether in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 247021
Summary Data
- G06 - Ames Summary Data (77 KB)
Genetic Toxicity Evaluation of bis(2-Chloro-1-methylethyl) Ether in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 856126
Summary Data
- G06 - Ames Summary Data (70 KB)
Genetic Toxicity Evaluation of bis(2-Chloro-1-methylethyl) Ether in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 891894
Summary Data
- G06 - Ames Summary Data (55 KB)