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Testing Status of Aspergillus fumigatus mold 08022



Short-Term Toxicity

  • 13 weeks (Inhalation)  (C08022)  Completed 
    • Subchronic Toxicity of Aspergillus fumigatus in B6C3F1/N Mice
    • Citation: Croston TL, Nayak AP, Lemons AR, Goldsmith WT, Gu JK, Germolec DR, Beezhold DH, Green BJ. Influence of Aspergillus fumigatus conidia viability on murine pulmonary microRNA and mRNA expression following subchronic inhalation exposure. Clin Exp Allergy. 2016;46(10):1315-1327
    • Citation: Nayak AP, Green BJ, Lemons AR, Marshall NB, Goldsmith WT, Kashon ML, Anderson SE, Germolec DR, Beezhold DH. Subchronic exposures to fungal bioaerosols promotes allergic pulmonary inflammation in naïve mice. Clin Exp Allergy. 2016 Jun;46(6):861-870
    • TOX-100 
      Toxicity Studies of Aspergillus fumigatus Administered by Inhalation to B6C3F1/N Mice (Revised)
    • Mice: B6C3F1
    • Dose: 0 (Air), Particle Control (1 x 10^5 Heat Killed Spores), 1 x 10^5 A. Fumigatus spores; 10 Male/10 Female.

Genetic Toxicology

  • 13 weeks Micronucleus (Inhalation)  (G08022)  Completed 
    • Female
    • Mice: B6C3F1
    • Male Negative 
    • Female Negative