Testing Status of Carbromal 10408-L
CASRN: 77-65-6
Formula: C7-H13-Br-N2-O2
Synonyms/Common Names
- Biogastrone
- N-(Aminocarbonyl)-2-bromo-2-ethylbutanamide
Short-Term Toxicity
- 14-Day (Dosed-Feed)
(C03805)
Completed
- Rats: F344/N; Mice: B6C3F1
- 13-Week (Dosed-Feed)
(C03805)
Completed
- Rats: F344/N; Mice: B6C3F1
- Dose: 0, 1470, 14700 PPM/5 PER GROUP.
Long-Term Carcinogenicity
- 2-Year (Dosed-Feed)
(C03805)
Completed
- TR-173 (NIH Number: 79-1729)
(Peer Review Approval 08/31/1978A )
Bioassay of Carbromal for Possible Carcinogenicity (CASRN 77-65-6) - Rats: F344/N; Mice: B6C3F1
- Carcinogenesis Results
- Male Rats Negative
- Female Rats Negative
- Male Mice Negative
- Female Mice Negative
- Dose: 0, 1250, 2500 PPM/50 PER GROUP.
- TR-173 (NIH Number: 79-1729)
(Peer Review Approval 08/31/1978A )
Genetic Toxicology
- In Vitro Cytogenetics (CA/SCE)
(157167)
Completed
- Sister Chromatid Exchange Negative
- Chromosome Aberrations Negative
- In Vitro Cytogenetics (CA/SCE)
(480465)
Completed
- Sister Chromatid Exchange Negative
- Chromosome Aberrations Positive
- Salmonella
(332501)
Completed
- Citation: Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
- Negative
- Salmonella
(652507)
Completed
- Citation: Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
- Negative