Testing Status of Phthalamide 10433-R
CASRN: 88-96-0
Formula: C8-H8-N2-O2
Synonyms/Common Names
- 1,2-Benzenedicarboxamide (9CI)
Short-Term Toxicity
- 13 weeks (Dosed-Feed)
(C03612)
Completed
- Rats: F344/N; Mice: B6C3F1
- Dose: 0, 6200, 50000 PPM/10 PER GROUP.
Long-Term Carcinogenicity
- 2 years (Dosed-Feed)
(C03612)
Completed
- TR-161 (NIH Number: 79-1717)
(Peer Review Approval 12/13/1978A )
Bioassay of Phthalamide for Possible Carcinogenicity (CASRN 88-96-0) - Rats: F344/N; Mice: B6C3F1
- Carcinogenesis Results
- Male Rats Negative
- Female Rats Negative
- Male Mice Negative
- Female Mice Negative
- Dose: MR: 0, 15000, 30000, FR: 0, 5000, 10000, MM: 0, 25000, 50000, FM: 0, 6250, 12500, 25000 PPM/50 PER GROUP.
- TR-161 (NIH Number: 79-1717)
(Peer Review Approval 12/13/1978A )
Genetic Toxicology
- In Vitro Cytogenetics (CA/SCE)
(869808)
Completed
- Sister Chromatid Exchange Negative
- Chromosome Aberrations Negative
- Mouse Lymphoma
(472127)
Completed
- Citation: McGregor, D., Brown, A., Cattanach, P., Edwards, I., McBride, D., Riach, C., and Caspary, W. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay: III. 72 coded chemicals. Environ. Molec. Mutagen. Vol. 12 (1988) 85-154
- Mice
- Negative
- Salmonella
(212698)
Completed
- Citation: Zeiger, E., Haworth, S., Mortelmans, K., and Speck, W. Mutagenicity testing of Di(2-ethylhexyl)phthalate and related chemicals in Salmonella Environ. Mutagen. Vol. 7 (1985) 213-232
- Negative