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Testing Status of Castor oil 10748-J

 

CASRN: 8001-79-4

Synonyms/Common Names

  • Phorbyol

Short-Term Toxicity

  • 13 weeks (Dosed-Feed)  (C55163B)  Completed 
    • TOX-12 (NIH Number: 92-3131)
      Toxicity Studies of Castor Oil (CASRN 8001-79-4) in F344/N Rats and B6C3F1 Mice (Dosed Feed Studies)
    • Rats: F344/N; Mice: B6C3F1
    • Dose: R&M:0, .62, 1.25, 2.5, 5.0, 10.0%.

Genetic Toxicology

  • In Vitro Cytogenetics (CA/SCE)  (154774)  Completed 
    • Sister Chromatid Exchange Negative 
    • Chromosome Aberrations Negative 
  • Micronucleus  (A74921)  Completed 
    • Citation: Witt, K.L., Knapton, A., Wehr, C.M., Hook, G.J., Mirsalis, J., Shelby, M.D., and MacGregor, J.T. Micronucleated Erythrocyte Frequency in Peripheral Blood of B6C3F1 Mice from Short-Term, Prechronic, and Chronic Studies of the NTP Carcinogenesis Bioassay Program. Environ. Molec. Mutagen. Vol. 36 (2000) 163-194
    • Mice: B6C3F1
    • Male Negative 
    • Female Negative 
  • Salmonella  (743044)  Completed 
    • Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelmans, K. Salmonella mutagenicity tests. IV. Results from the testing of 300 chemicals Environ. Molec. Mutagen. Vol. 11 (Suppl 12) (1988) 1-158
    •  Negative