Testing Status of Dibromoacetonitrile 10985-P

CASRN: 3252-43-5

Formula: C2-H-Br2-N

Synonyms/Common Names

• Dibromoacetonitrile

Special Studies

• Absorption Distribution Metabolism Excretion (Gavage; Intravenous; Gavage; Intravenous)  (S0820)  Completed 
  • Male Rats: F344/N; Male Mice: B6C3F1
  • Dose: (all routes) 0.2, 2 and 20 mg/kg [R,M].

Genetic Toxicology

• Drosophila  (369991)  Completed 
  • Citation: Valencia, R., Mason, J.M., Woodruff, R.C., and Zimmering, S. Chemical mutagenesis testing in Drosophila: III. Results of 48 coded compounds tested for the National Toxicology Program. Environ. Mutagen. Vol. 7 (1985) 325-348
  • Reciprocal Translocation/Sex-Linked Recessive Lethal Negative 
• Micronucleus  (A00107)  Completed 
  • Mice: B6C3F1
  • Male Negative 
  • Female Negative 
• Salmonella  (298559)  Completed 
  • Citation: Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
  •  Weakly Positive 
• Salmonella  (450116)  Completed 
  •  Weakly Positive 
• Salmonella  (573952)  Completed 
  •  Equivocal 
• Salmonella  (877154)  Completed 
  • Citation: Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
  •  Weakly Positive 
• Salmonella  (A44565)  Completed 
  •  Positive 

Organ Systems Toxicity

• 35 days Repro/Dev Gen Tox (28-Day) (Dosed-Water)  (RDGT94014)  Completed 
  • Male and Female Rats: Sprague Dawley
  • Dose: 0, 15, 50, OR 150 PPM.