Skip to Main Navigation
Skip to Page Content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Testing Status of beta-Thioguanidine deoxyriboside C01581

 

CASRN: 789-61-7

Formula: C10-H13-N5-O3-S

Synonyms/Common Names

  • beta-TGdR
  • 2'-Deoxy-6-thioguanosine (9CI)

Short-Term Toxicity

  • 14-Day (Intraperitoneal Injection)  (C01581)  Completed 
    • Rats: Sprague Dawley; Mice: B6C3F1
  • 13-Week (Intraperitoneal Injection)  (C01581)  Completed 
    • Rats: Sprague Dawley; Mice: B6C3F1
    • Dose: R: 0, 3, 60, M: 0, .38, 3 MG/KG/5 PER GROUP.

Long-Term Carcinogenicity

  • 2-Year (Intraperitoneal Injection)  (C01581)  Completed 
    • TR-057 (NIH Number: 78-1363)  (Peer Review Approval 02/18/1978A )
      Bioassay of ß-TGdR for Possible Carcinogenicity (CASRN 789-61-7)
    • Rats: Sprague Dawley; Mice: B6C3F1
    • Carcinogenesis Results
      • Male Rats Equivocal 
      • Female Rats Positive 
      • Male Mice Inadequate Study 
      • Female Mice Inadequate Study 
    • Dose: R: 0, 3.5, 7, M: 0, 1, 4 MG/KG/35 PER GROUP.