Testing Status of 1,1-Dichloroethane C04535
CASRN: 75-34-3
Formula: C2-H4-Cl2
Synonyms/Common Names
- Ethylidene dichloride
Short-Term Toxicity
- 14-Day (Gavage)
(C04535)
Completed
- Rats: Osborne Mendel; Mice: B6C3F1
- 13-Week (Gavage)
(C04535)
Completed
- Rats: Osborne Mendel; Mice: B6C3F1
- Dose: R: 0, 562, 5620, M: 0, 1000, 10000 MG/KG/5 PER GROUP.
Long-Term Carcinogenicity
- 2-Year (Gavage)
(C04535)
Completed
- TR-066 (NIH Number: 78-1316)
(Peer Review Approval 01/18/1978A )
Bioassay of 1,1-Dichloroethane for Possible Carcinogenicity (CASRN 75-34-3) - Rats: Osborne Mendel; Mice: B6C3F1
- Carcinogenesis Results
- Male Rats Negative
- Female Rats Equivocal
- Male Mice Negative
- Female Mice Equivocal
- Dose: MR: 0, 382, 764 (AVG), FR: 0, 475, 950 (AVG), MM: 0, 1442, 2885 (AVG), FM: 0, 1665, 3331 (AVG) MG/KG/50 PER GROUP.
- TR-066 (NIH Number: 78-1316)
(Peer Review Approval 01/18/1978A )
Genetic Toxicology
- In Vitro Cytogenetics (CA/SCE)
(508873)
Completed
- Sister Chromatid Exchange Positive
- Chromosome Aberrations Negative
- Salmonella
(777132)
Completed
- Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelman, K. Salmonella Mutagenicity Tests V. Results from the Testing of 311 Chemicals Environ. Molec. Mutagen. Vol. 19 (Suppl 21) (1992) 2-141
- Negative