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Testing Status of Transgenic model evaluation II (Glycidol) M990070

 

CASRN: 556-52-5

Formula: C3-H6-O2

Synonyms/Common Names

  • Glycidol (Transgenic model evaluation II)
  • Oxiranemethanol (9CI)

Short-Term Toxicity

  • 40 weeks (Gavage)  (C99035)  Completed 
    • GMM-13 (NIH Number: 08-5962)  (Peer Review Approval 08/28/2006A )
      Toxicology and Carcinogenesis Study of Glycidol (CASRN 556-52-5) in Genetically Modified Haploinsufficient p16Ink4a/p19Arf Mice (Gavage Study)
    • Mice: P16(Ink4a)/(+/-) (C57BL/6)
    • Carcinogenesis Results
      • Male Clear Evidence 
      • Female Some Evidence 
    • Dose: 0, 25, 50, 100, OR 200 MG/KG.