DrugMatrix/ToxFX

The DrugMatrix database is one of the world’s largest toxicogenomic reference resources. The ToxFX reporting system, a companion to DrugMatrix, allows users to quickly create fully annotated reports from DrugMatrix data. Together, these tools increase the efficiency of the toxicological assessment process and reduce the amount of time needed to formulate a xenobiotic’s potential for toxicity.

While NTP no longer hosts the original DrugMatrix web application and ToxFX application for external users, we do offer the following
resources:

• DrugMatrix Source Code
• ToxFX Source Code
• DrugMatrix PathxGene

These DrugMatrix and ToxFX resources provide access to the toxicogenomic profiles of over 600 different compounds. In addition, the Gene Expression Omnibus Database contains DrugMatrix gene expression data, including the following microarrays:

• Affymetrix
  • Liver
  • Kidney
  • Thigh Muscle
  • Heart
  • Cultured Hepatocytes
• Codelink
  • Liver
  • Kidney
  • Thigh Muscle
  • Heart
  • Bone Marrow
  • Spleen
  • Intestine
  • Brain
  • Cultured Hepatocytes