Dicyclohexylcarbodiimide: Target Organs and Levels of Evidence for GMM-09
Toxicology Studies of Dicyclohexylcarbodiimide (CASRN 538-75-0) in F344/N Rats, B6C3F1 Mice, and Genetically Modified (FVB Tg.AC HEMIZYGOUS) Mice and Carcinogenicity Study of Dicyclohexylcarbodiimide in Genetically Modified [B6.129-Trp53tm1Brd (N5) Haploinsufficient] Mice (Dermal Studies)
Chemical (Study Title) CASRN | Peer Review Date | Route/Exposure Levels | Study Laboratory |
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Dicyclohexylcarbodiimide 538-75-0 | 08/28/2006 | Topical Application 0, 0.75, 1.5, 3, 6, or 12 mg/kg; 15/group | BioReliance, Inc |
Female Tg.AC Hemizygous Mice | |
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20 Week | |
Neoplastic Lesions |
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Non-Neoplastic Lesions |
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Female p53 Haploinsufficient Mice | |
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27 Week | |
Levels of Evidence | No evidence |
Neoplastic Lesions | None |
Non-Neoplastic Lesions |
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