TDMS Study 96003-04 Pathology Tables
NTP Experiment-Test: 96003-04 INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (a) Report: PEIRPT02
Study Type: 39 WEEKS ALLYL BROMIDE Date: 03/26/01
Route: GAVAGE Time: 13:45:32
FINAL#1/MICE
Facility: BIORELIANCE
Chemical CAS #: 106-95-6
Lock Date: 10/18/00
Cage Range: All
Reasons For Removal: All
Removal Date Range: All
Treatment Groups: Include All
a Number of animals examined microscopically at site and number of animals with lesion
Page 1
NTP Experiment-Test: 96003-04 INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (a) Report: PEIRPT02
Study Type: 39 WEEKS ALLYL BROMIDE Date: 03/26/01
Route: GAVAGE Time: 13:45:32
____________________________________________________________________________________________________________________________________
MICE:FVB/N FEMALE VEHICLE 8 MG/KG
CONTROL
____________________________________________________________________________________________________________________________________
DISPOSITION SUMMARY
Animals Initially in Study 15 15
Early Deaths
Moribund Sacrifice 1
Survivors
Terminal Sacrifice 15 14
Animals Examined Microscopically 15 15
____________________________________________________________________________________________________________________________________
ALIMENTARY SYSTEM
None
____________________________________________________________________________________________________________________________________
CARDIOVASCULAR SYSTEM
None
____________________________________________________________________________________________________________________________________
ENDOCRINE SYSTEM
None
____________________________________________________________________________________________________________________________________
GENERAL BODY SYSTEM
None
____________________________________________________________________________________________________________________________________
GENITAL SYSTEM
None
____________________________________________________________________________________________________________________________________
HEMATOPOIETIC SYSTEM
None
____________________________________________________________________________________________________________________________________
Page 2
NTP Experiment-Test: 96003-04 INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (a) Report: PEIRPT02
Study Type: 39 WEEKS ALLYL BROMIDE Date: 03/26/01
Route: GAVAGE Time: 13:45:32
____________________________________________________________________________________________________________________________________
MICE:FVB/N FEMALE VEHICLE 8 MG/KG
CONTROL
____________________________________________________________________________________________________________________________________
INTEGUMENTARY SYSTEM
None
____________________________________________________________________________________________________________________________________
MUSCULOSKELETAL SYSTEM
None
____________________________________________________________________________________________________________________________________
NERVOUS SYSTEM
None
____________________________________________________________________________________________________________________________________
RESPIRATORY SYSTEM
Lung (15) (15)
Alveolar/Bronchiolar Adenoma 2 (13%) 1 (7%)
____________________________________________________________________________________________________________________________________
SPECIAL SENSES SYSTEM
None
____________________________________________________________________________________________________________________________________
URINARY SYSTEM
None
Page 3
NTP Experiment-Test: 96003-04 INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (a) Report: PEIRPT02
Study Type: 39 WEEKS ALLYL BROMIDE Date: 03/26/01
Route: GAVAGE Time: 13:45:32
____________________________________________________________________________________________________________________________________
MICE:FVB/N FEMALE VEHICLE 8 MG/KG
CONTROL
____________________________________________________________________________________________________________________________________
TUMOR SUMMARY
Total Animals with Primary Neoplasms (b) 2 1
Total Primary Neoplasms 2 1
Total Animals with Benign Neoplasms 2 1
Total Benign Neoplasms 2 1
Total Animals with Malignant Neoplasms
Total Malignant Neoplasms
Total Animals with Metastatic Neoplasms
Total Metastatic Neoplasm
Total Animals with Malignant Neoplasms
Uncertain Primary Site
Total Animals with Neoplasms Uncertain-
Benign or Malignant
Total Uncertain Neoplasms
____________________________________________________________________________________________________________________________________
a Number of animals examined microscopically at site and number of animals with lesion
b Primary tumors: all tumors except metastatic tumors
Page 4
NTP Experiment-Test: 96003-04 INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (a) Report: PEIRPT02
Study Type: 39 WEEKS ALLYL BROMIDE Date: 03/26/01
Route: GAVAGE Time: 13:45:32
____________________________________________________________________________________________________________________________________
MICE:FVB/N MALE VEHICLE 8 MG/KG
CONTROL
____________________________________________________________________________________________________________________________________
DISPOSITION SUMMARY
Animals Initially in Study 15 15
Early Deaths
Dosing Accident 1
Survivors
Terminal Sacrifice 15 14
Animals Examined Microscopically 15 15
____________________________________________________________________________________________________________________________________
ALIMENTARY SYSTEM
None
____________________________________________________________________________________________________________________________________
CARDIOVASCULAR SYSTEM
None
____________________________________________________________________________________________________________________________________
ENDOCRINE SYSTEM
None
____________________________________________________________________________________________________________________________________
GENERAL BODY SYSTEM
None
____________________________________________________________________________________________________________________________________
GENITAL SYSTEM
None
____________________________________________________________________________________________________________________________________
HEMATOPOIETIC SYSTEM
None
____________________________________________________________________________________________________________________________________
Page 5
NTP Experiment-Test: 96003-04 INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (a) Report: PEIRPT02
Study Type: 39 WEEKS ALLYL BROMIDE Date: 03/26/01
Route: GAVAGE Time: 13:45:32
____________________________________________________________________________________________________________________________________
MICE:FVB/N MALE VEHICLE 8 MG/KG
CONTROL
____________________________________________________________________________________________________________________________________
INTEGUMENTARY SYSTEM
None
____________________________________________________________________________________________________________________________________
MUSCULOSKELETAL SYSTEM
None
____________________________________________________________________________________________________________________________________
NERVOUS SYSTEM
None
____________________________________________________________________________________________________________________________________
RESPIRATORY SYSTEM
Lung (15) (15)
Alveolar/Bronchiolar Adenoma 2 (13%)
Alveolar/Bronchiolar Adenoma, Multiple 1 (7%)
____________________________________________________________________________________________________________________________________
SPECIAL SENSES SYSTEM
None
____________________________________________________________________________________________________________________________________
URINARY SYSTEM
None
Page 6
NTP Experiment-Test: 96003-04 INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (a) Report: PEIRPT02
Study Type: 39 WEEKS ALLYL BROMIDE Date: 03/26/01
Route: GAVAGE Time: 13:45:32
____________________________________________________________________________________________________________________________________
MICE:FVB/N MALE VEHICLE 8 MG/KG
CONTROL
____________________________________________________________________________________________________________________________________
TUMOR SUMMARY
Total Animals with Primary Neoplasms (b) 3
Total Primary Neoplasms 3
Total Animals with Benign Neoplasms 3
Total Benign Neoplasms 3
Total Animals with Malignant Neoplasms
Total Malignant Neoplasms
Total Animals with Metastatic Neoplasms
Total Metastatic Neoplasm
Total Animals with Malignant Neoplasms
Uncertain Primary Site
Total Animals with Neoplasms Uncertain-
Benign or Malignant
Total Uncertain Neoplasms
____________________________________________________________________________________________________________________________________
a Number of animals examined microscopically at site and number of animals with lesion
b Primary tumors: all tumors except metastatic tumors
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